Paraskevi, T., S. Jolien, S. Wendy, S. Adria, D. Katarina Stoklund, C. Adriana Margarida Barbosa, P. Arun, H. Andreas, D. Philip Van, M. Thomas and B. Ludo Van Den, 2023. PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. bioRxiv: 2023.2008.2028.555106. https://doi.org/10.1101/2023.08.28.555106
Tags: hiPSC-derived motor neurons, myoblasts, neuromuscular junction (NMJ), preprint, XC150
Costamagna, D., V. Bastianini, M. Corvelyn, R. Duelen, J. Deschrevel, N. De Beukelaer, H. De Houwer, M. Sampaolesi, G. Gayan-Ramirez, A. V. Campenhout and K. Desloovere, 2023. Botulinum Toxin Treatment of Adult Muscle Stem Cells from Children with Cerebral Palsy and hiPSC-Derived Neuromuscular Junctions. Cells 12 DOI: 10.3390/cells12162072. https://doi.org/10.3390/cells12162072
Tags: hiPSC-derived, lower motor neurons, myoblasts, neuromuscular junction (NMJ), XC150
Stoklund Dittlau, K., Terrie, L., Baatsen, P., Kerstens, A., De Swert, L., Janky, R.s., Corthout, N., Masrori, P., Van Damme, P., Hyttel, P., Meyer, M., Thorrez, L., Freude, K., Van Den Bosch, L., 2023. FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms. Molecular Neurodegeneration 18, 5. * uses XonaChips® (XC150) with co-culture of hiPSC-derived motor neurons and astrocytes with human primary myoblasts. https://doi.org/10.1186/s13024-022-00591-3
Tags: astrocytes, co-culture, hiPSC-derived motor neurons, myoblasts, XC150
Limone, F., Guerra San Juan, I., Mitchell, J.M., Smith, J.L.M., Raghunathan, K., Meyer, D., Ghosh, S.D., Couto, A., Klim, J.R., Joseph, B.J., Gold, J., Mello, C.J., Nemesh, J., Smith, B.M., Verhage, M., McCarroll, S.A., Pietiläinen, O., Nehme, R., Eggan, K., 2023. Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues. Cell Reports 42, 111896.
* uses XonaChips® (XC450) with co-culture of human lower induced motor neurons (liMNs) and primary murine myoblasts. https://doi.org/10.1016/j.celrep.2022.111896
Tags: co-culture, hiPSC-derived motor neurons, myoblasts, XC450
Costamagna, D., Casters, V., Beltrà, M., Sampaolesi, M., Van Campenhout, A., Ortibus, E., Desloovere, K., Duelen, R., 2022. Autologous iPSC-Derived Human Neuromuscular Junction to Model the Pathophysiology of Hereditary Spastic Paraplegia, Cells. * uses XonaChips® (XC150) with human iPSC-differentiated lower motor neurons and myoblasts to create in vitro NMJs. https://doi.org/10.3390/cells11213351
Tags: hereditary spastic paraplegia, hiPSC-derived motor neurons, lower motor neurons, myoblasts, neuromuscular junction (NMJ), XC150