NIH-FUNDED RESEARCH

In addition to our commercial operations, Xona Microfluidics performs grant-funded research. We believe focusing on research together with our commercial activities is critical for our success.

Current projects:

Grant #: R43AG072985                        Taylor, Anne Marion (PI)     02/2022-01/2024

Funding agency: NIA

Title: Tau mislocalization assay to screen AD therapeutics using compartmentalized chips

The goal of this project is to develop a scalable and reliable cell-based test that models cellular dysfunction in
Alzheimer’s disease. This project is relevant to public health because it seeks to facilitate and speed up
therapeutic discovery to treat Alzheimer’s disease.

Grant #: R21NS109750                         Taylor, Anne Marion (PI)     04/2020-03/2022

Funding agency: NINDS

Title: The influence of axonal ER on retrograde synapse loss following axon damage

The goal of this project is to investigate calcium-dependent axon-to-soma signaling following axotomy that causes somatic ER changes and synapse loss.

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Completed projects:

Grant #: R41NS108895                         Taylor, Anne Marion (PI)                         09/2018-08/2020

Funding agency: NINDS

Title: A user-friendly microfluidic chip for anti-epileptogenic drug screening

The goal of this grant is to develop a new anti-epileptogenic drug screen using Xona’s patented platform technology.

Grant #: R42MH097377                       Taylor, Anne Marion (PI)                         05/2013-09/2019

Funding agency: NIMH

Title: A user-friendly scalable microfluidic platform for enhanced neuron-cell culture

The goal of this grant is to develop user-friendly and robust technology for neuron-cell culture including the development of novel technology for human stem cell-derived neurons and to examine and manipulate synapses.

 For more information visit: https://reporter.nih.gov/search/o558IfNKaUCrM4NZmQO7TQ/projects?shared=true