Akiyama T, Zeng Y, Guo C, Gautier O, Koepke L, Bombosch J, Sianto O, Ross JP, Hoang PT, Zhao LY, Spencer C, Monje M, Day JW, Gitler AD. KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS. bioRxiv [Preprint]. 2025 Jul 13:2025.07.11.664426. doi: 10.1101/2025.07.11.664426. PMID: 40672150; PMCID: PMC12265700.
Tags: i3Neurons, XC450
Ricci, C., M. J. Midroit, F. Caicci, T. Achsel, N. Domínguez-Iturza and C. Bagni (2025). "CYFIP1 governs the development of cortical axons by modulating calcium availability." Nature Communications 16(1): 10764. https://doi.org/10.1038/s41467-025-65801-0
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Han, X., V. Petrova, Y. Song, Y.-T. Cheng, X. Jiang, H. Zhou, C. Hu, D. S. Chen, H. J. Yong, H. W. Kim, B. Zhang, O. Barkai, A. Jain, W. Renthal, P. Lirk, C. J. Woolf and J. Shi (2025). "Lipid nanoparticle delivery of siRNA to dorsal root ganglion neurons to treat pain." bioRxiv: 2025.2001.2023.633455. https://doi.org/10.1101/2025.01.23.633455
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Gomes, C., K.-C. Huang, S. S. Lavekar, J. Harkin, C. G. Prosser, Y. Fang, C. Kalem, A. Oblak, C. Zhang and J. S. Meyer (2025). "Modeling human retinal ganglion cell axonal outgrowth, development, and pathology using pluripotent stem cell–based microfluidic platforms." Proceedings of the National Academy of Sciences 122(37): e2423682122. https://doi.org/10.1073/pnas.2423682122
Tags: hiPSC-derived, retinal organoid, XC-T500, XC450
Fullam, S., D. Ren, A. Belmadani, D. Hoffman, R. Miller, A.-M. Malfait and R. Miller (2025). "A Novel System for Micro-Mechanical Stimulation of Sensory Neuron Axons in Microfluidic Devices." The Journal of Pain 29. https://doi.org/10.1016/j.jpain.2025.104901
Koch, M., M. Kshirsagar, A. Rawat, A. Zare, F. Schlott, T. Bischler, P. Arampatzi, M. Briese and M. Sendtner (2025). "NGF stimulation alters the transcriptome and surface TrkB expression in axons of dorsal root ganglion neurons." Neurobiology of Pain 18: 100194. https://doi.org/10.1016/j.ynpai.2025.100194
Tags: IND150
Zare, A., S. Salehi, J. M. Bader, A.-L. Wiessler, M. Prokesch, V. Albrecht, C. Villmann, M. Mann, M. Briese and M. Sendtner (2025). "Axonal tau reduction ameliorates tau and amyloid pathology in a mouse model of Alzheimer’s disease." Translational Neurodegeneration 14(1): 39. https://doi.org/10.1186/s40035-025-00499-0
Tags: IND150
Xu, J., M. Hörner, M. Nagel, P. Perhat, M. Korneck, M. Noß, S. Hauser, L. Schoels, J. Admard, N. Casadei and R. Schuele (2025). "Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration." Open Biology 15(6): 250101. https://doi.org/10.1098/rsob.250101
Park, S. J., N. Lee, I. H. Wang, H.-C. Jiang, T. Luu, T. Uemura, K. Futai, D. Kim, E. Macosko and P. Greer (2025). "The neurexin gene family regulates olfactory glomerular formation." Cell Reports 44(8). https://doi.org/10.1016/j.celrep.2025.116125
Tags: SND150
Mamberti, S., C. Pesce, G. Avancini, G. Somu Naidu, G. R. Kundoor, C. Portioli, D. Peer, P. Decuzzi and R. Palomba (2025). "On The Retrograde Transport of RNA-Loaded Lipid Nanoparticles Designed for Brain Delivery." ACS Nanoscience Au. https://doi.org/10.1021/acsnanoscienceau.5c00042
Tags: XC150
Wang, K. S., J. Smeyers, K. Eggan, B. Budnik and D. A. Mordes (2025). "C9ORF72 poly-PR disrupts expression of ALS/FTD-implicated STMN2 through SRSF7." Acta Neuropathologica Communications 13(1): 67. https://doi.org/10.1186/s40478-025-01977-2
Tags: SND150
Dai, L., J. Wang, L. Meng, X. Zhang, T. Xiao, M. Deng, G. Chen, J. Xiong, W. Ke, Z. Hong, L. Bu and Z. Zhang (2025). "The cholesterol 24-hydroxylase CYP46A1 promotes α-synuclein pathology in Parkinson’s disease." PLOS Biology 23(2): e3002974. https://doi.org/10.1371/journal.pbio.3002974
Tags: RD150
Heo, K., T. S.-Y. Ho, X. Zeng, B. L. Turnes, M. Arab, S. Jayakar, K. Chen, G. Kimourtzis, M. C. Condro, E. Fazzari, X. Song, J. Tabitha Hees, Z. Xu, X. Chen, L. B. Barrett, L. Perrault, R. Pandey, K. Zhang, A. Bhaduri, Z. He, H. I. Kornblum, J. Hubbs and C. J. Woolf (2025). "Non-muscle myosin II inhibition at the site of axon injury increases axon regeneration." Nature Communications 16(1): 2975. https://doi.org/10.1038/s41467-025-58303-6
Tags: SND450
Peng, C. S., Y. Zhang, Q. Liu, G. E. Marti, Y.-W. A. Huang, T. C. Südhof, B. Cui and S. Chu (2025). "Nanometer-resolution tracking of single cargo reveals dynein motor mechanisms." Nature Chemical Biology 21(5): 648-656. https://doi.org/10.1038/s41589-024-01694-2
Tags: SND900
Ahmad, S., T. Christova, M. Pye, M. Narimatsu, S. Song, J. L. Wrana and L. Attisano (2025) "Small Extracellular Vesicles Promote Axon Outgrowth by Engaging the Wnt-Planar Cell Polarity Pathway." Cells 14 DOI: 10.3390/cells14010056. https://doi.org/10.3390/cells14010056
Tags: XC150
Scholz, K., R. Pattanayak, R. Ekkatine, F. S. Pair, A. Nobles, W. J. Stone and T. A. Yacoubian (2025). "Rab27b Promotes Lysosomal Function and Alpha-Synuclein Clearance in Neurons." The Journal of Neuroscience 45(14): e1579242025. https://doi.org/10.1523/JNEUROSCI.1579-24.2025
Ren, Z., W. Huang, X. Gu and L. Zhao (2025). "AT-rich interaction domain 5A facilitates axon regeneration through docking protein 6 in the peripheral nervous system." Burns & Trauma 13: tkaf012. https://doi.org/10.1093/burnst/tkaf012
Tags: SND150
Jinno, J., R. F. Abdelhamid, J. Morita, R. Saga, Y. Yamasaki, A. Kadowaki, K. Ogawa, Y. Kimura, K. Ikenaka, G. Beck, K. Baba, Y. Nagai, E. Kasahara, A. Sekiyama, T. Hirayama, I. Hozumi, T. Hasegawa, T. Araki, H. Mochizuki and S. Nagano (2025). "TDP-43 transports ferritin heavy chain mRNA to regulate oxidative stress in neuronal axons." Neurochemistry International 184: 105934. https://doi.org/10.1016/j.neuint.2025.105934
Tags: XC450
Cong, M., J.-J. Hu, Y. Yu, X.-L. Li, X.-T. Sun, L.-T. Wang, X. Wu, L.-J. Zhu, X.-J. Yang, Q.-R. He, F. Ding and H.-Y. Shi (2025). "miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow–derived neural crest cells." Neural Regeneration Research 20(1). https://journals.lww.com/nrronline/toc/2025/01000
Tags: SND450
Habib, M., A.-L. Wiessler, P. Fischer, M. Niesner, M. Selcho, L. Abrante, C. Werner, A. Sodmann, M. Koch, A. Zare, H. Prüss, J. Dargvainiene, J. Lewerenz, R. Handreka, P. Körtvelyessy, D. Reinhold, F. S. Thaler, K. Pitarokoili, R. J. Kittel, M. Briese, M. Sendtner, H. Rittner, F. Leypoldt, C. Sommer, R. Blum, K. Doppler and C. Villmann "Neuropathic Pain and Distinct CASPR2 Autoantibody IgG Subclasses Drive Neuronal Hyperexcitability." Neurology Neuroimmunology & Neuroinflammation 12(4): e200423. https://doi.org/10.1212/NXI.0000000000200423
Tags: IND150
Yang, L., J. Du, S. Jin, S. Yang, Z. Chen, S. Yu, C. Fan, C. Zhou and H. Ruan (2025). "Chirality-Induced Hydroxyapatite Manipulates Enantioselective Bone-Implant Interactions Toward Ameliorative Osteoporotic Osseointegration." Advanced Science 12(8): 2411602. https://doi.org/10.1002/advs.202411602
Zhang, Y., Z. Liu, M. Chopp, M. Millman, Y. Li, P. Cepparulo, A. Kemper, C. Li, L. Zhang and Z. G. Zhang (2025). "Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery." Neural Regeneration Research 20(1). https://journals.lww.com/nrronline/toc/2025/01000
Tags: SND450
Uechi, H., S. Sridharan, J. Nijssen, J. Bilstein, J. M. Iglesias-Artola, S. Kishigami, V. Casablancas-Antras, I. Poser, E. J. Martinez, E. Boczek, M. Wagner, N. Tomschke, A. M. de Jesus Domingues, A. Pal, T. Doeleman, S. Kour, E. N. Anderson, F. Stein, H. O. Lee, X. Zhang, A. W. Fritsch, M. Jahnel, J. Fürsch, A. C. Murthy, S. Alberti, M. Bickle, N. L. Fawzi, A. Nadler, D. C. David, U. B. Pandey, A. Hermann, F. Stengel, B. G. Davis, A. J. Baldwin, M. M. Savitski, A. A. Hyman and R. J. Wheeler (2025). "Small-molecule dissolution of stress granules by redox modulation benefits ALS models." Nature Chemical Biology. https://doi.org/10.1038/s41589-025-01893-5
Tags: RD900
Qin, T., Y. Jin, Y. Qin, F. Yuan, H. Lu, J. Hu, Y. Cao and C. Li (2025). "Enhancing m6A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury." Neural Regeneration Research 20(6). https://journals.lww.com/nrronline/toc/2025/06000
Tags: primary, SND450
Han, M., M. L. Fu, Y. Zhu, A. A. Choi, E. Li, J. Bezney, S. Cai, L. Miles, Y. Ma and L. S. Qi (2025). "Programmable control of spatial transcriptome in live cells and neurons." Nature 643(8070): 241-251. https://doi.org/10.1038/s41586-025-09020-z
Tags: SND450
Taguchi, K., Y. Watanabe and M. Tanaka (2025). "SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation." iScience 28(2). https://doi.org/10.1016/j.isci.2025.111935
Tags: primary, TCND500