Li, C., Zhang, Y., Levin, A.M., Fan, B.Y., Teng, H., Ghannam, M.M., Chopp, M., Zhang, Z.G., 2019. Distal Axonal Proteins and Their Related MiRNAs in Cultured Cortical Neurons. Mol Neurobiol. Apr;56(4):2703-2713. doi: 10.1007/s12035-018-1266-7. * uses Xona’s Silicone Devices (SND450) with rat cortical neurons
Tags: cortical neurons, rat, SND450

Fantuzzo, J.A., Hart, R.P., Zahn, J.D., Pang, Z.P., 2019. Compartmentalized Devices as Tools for Investigation of Human Brain Network Dynamics. Dev Dyn 248, 65-77. doi: 10.1002/dvdy.2466 * Review paper
Tags: review

Klim, J.R., Williams, L.A., Limone, F., Guerra San Juan, I., Davis-Dusenbery, B.N., Mordes, D.A., Burberry, A., Steinbaugh, M.J., Gamage, K.K., Kirchner, R., Moccia, R., Cassel, S.H., Chen, K., Wainger, B.J., Woolf, C.J., Eggan, K., 2019. ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nat Neurosci. Feb;22(2):167-179. doi: 10.1038/s41593-018-0300-4. * uses Xona’s Silicone Devices (SND150) with human stem cell (iPSC and ESC) derived motor neurons
Tags: human, motor neurons, SND150, stem cells

Zhu, S., Zhu, J., Zhen, G., Hu, Y., An, S., Li, Y., Zheng, Q., Chen, Z., Yang, Y., Wan, M., Skolasky, R.L., Cao, Y., Wu, T., Gao, B., Yang, M., Gao, M., Kuliwaba, J., Ni, S., Wang, L., Wu, C., Findlay, D., Eltzschig, H.K., Ouyang, H.W., Crane, J., Zhou, F.-Q., Guan, Y., Dong, X., Cao, X., 2019. Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain. J Clin Invest. 2019 Mar 1;129(3):1076-1093. doi: 10.1172/JCI121561 * uses Xona’s Silicone Devices (SND450) with mouse DRG neurons
Tags: DRG, mouse, SND450

Wang, L., Chopp, M., Lu, X., Szalad, A., Jia, L., Liu, X.S., Wu, K.-H., Lu, M., Zhang, Z.G., 2019. miR-146a mediates thymosin β4 induced neurovascular remodeling of diabetic peripheral neuropathy in type-II diabetic mice. Brain Res. Mar 15;1707:198-207. doi: 10.1016/j.brainres.2018.11.039 * uses Xona’s Silicone Devices (Cat. # not specified) with rat DRG neurons
Tags: DRG, rat, SND450

Bieri, G., Brahic, M., Bousset, L., Couthouis, J., Kramer, N.J., Ma, R., Nakayama, L., Monbureau, M., Defensor, E., Schüle, B., Shamloo, M., Melki, R., Gitler, A.D., 2019. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.  Acta Neuropathol. 2019 Mar 29. doi: 10.1007/s00401-019-01995-0. * uses Xona’s Silicone Devices (SND450) with human stem cell derived neurons
Tags: human, SND450, stem cells

Kamande, J.W., Nagendran, T., Harris, J., Taylor, A.M., 2019. Multi-compartment Microfluidic Device Geometry and Covalently Bound Poly-D-Lysine Influence Neuronal Maturation. Front. Bioeng. Biotechnol. | doi: 10.3389/fbioe.2019.00084. * uses Xona’s Silicone Devices (SND450, DOC450) with human stem cell derived glutamatergic neurons **Original research authored by Xona scientists**
Tags: DOC450, glutamatergic, hiPSC-derived, human, SND450, Xona author

Zheng, Y., Zhang, X., Wu, X., Jiang, L., Ahsan, A., Ma, S., Xiao, Z., Han, F., Qin, Z.-H., Hu, W., Chen, Z., 2019. Somatic autophagy of axonal mitochondria in ischemic neurons. The Journal of cell biology 218, 1891-1907. doi: 10.1083/jcb.201804101 * uses Xona’s Silicone Devices (RD450) with mouse cortical neurons
Tags: cortical neurons, mouse, RD450

Pu, H., Shi, Y., Zhang, L., Lu, Z., Ye, Q., Leak, R.K., Xu, F., Ma, S., Mu, H., Wei, Z., Xu, N., Xia, Y., Hu, X., Hitchens, T.K., Bennett, M.V.L., Chen, J., 2019. Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke. Proceedings of the National Academy of Sciences 116, 9115, doi: 10.1073/pnas.1821979116.* uses Xona’s Silicone Devices (SND450) with rat cortical neurons
Tags: cortical neurons, rat, SND450

Paranjape, S. R., Nagendran, T., Poole, V., Harris, J., Taylor, A. M. (2019). Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips J. Vis. Exp. (147), e59250, doi:10.3791/59250 (2019). * uses XonaChips® (XC150, XC450, XC900) with human stem cell derived glutamatergic neurons **authored by Xona scientists
Tags: glutamatergic, hiPSC-derived, human, protocol, XC150, XC450, XC900, Xona author

Yan, K., Liu, J., Guan, X., Yin, Y. X., Peng, H., Chen, H. C., & Liu, Z. F. (2019). The Carboxyl Terminus of Tegument Protein pUL21 Contributes to Pseudorabies Virus Neuroinvasion. Journal of virology, 93(7), e02052-18. * uses Xona’s Silicone Devices (SND450) with chicken DRG neurons
Tags: chicken, DRG, SND450

Hixon, A. M., Clarke, P., & Tyler, K. L. (2019). Contemporary Circulating Enterovirus D68 Strains Infect and Undergo Retrograde Axonal Transport in Spinal Motor Neurons Independent of Sialic Acid. Journal of virology93(16), e00578-19. * uses Xona’s Silicone Devices (RD450) with human iPSC-derived motor neurons
Tags: hiPSC-derived motor neurons, human, RD450

Desforges, M., Le Coupanec, A., Dubeau, P., Bourgouin, A., Lajoie, L., Dubé, M., & Talbot, P. J. (2019). Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?. Viruses12(1), 14. * uses XonaChips® (XC150) with murine mixed neurons
Tags: cortical neurons, mouse, rat, XC150

Nagendran, T. & Taylor, A.M. (2019). Unique Axon-to-Soma Signaling Pathways Mediate Dendritic Spine Loss and Hyper-Excitability Post-axotomy. Front. Cell. Neurosci., 13(431), * uses Silicone Devices (SND900) with rat hippocampal neurons **Original research authored by Xona scientists**
Tags: hippocampal neurons, rat, SND900, Xona author

Vysokov, N., McMahon, S.B., Raouf, R., 2019. The role of NaV channels in synaptic transmission after axotomy in a microfluidic culture platform. Sci Rep 9, 12915. DOI: 10.1038/s41598-019-49214-w * uses Xona’s Silicone Devices (TCND1000) with rat DRG neurons and dorsal horn co-culture
Tags: co-culture, dorsal horn, DRG, rat, TCND1000

Shekari, A. & Fahnestock, M. (2019). Retrograde axonal transport of BDNF and proNGF diminishes with age in basal forebrain cholinergic neurons. Neurobiol. Aging, 84: 131-140, * uses XonaChips® (XC450) with rat basal forebrain or cortical neurons
Tags: basal forebrain cholinergic neurons, cortical neurons, rat, XC450

Nijssen, J., Aguila, J. and Hedlund, E. (2019). Axon-seq for in Depth Analysis of the RNA Content of Neuronal Processes. Bio-protocol 9(14): e3312. DOI: 10.21769/BioProtoc.3312. * uses Xona’s Silicone Devices (SND150, SND450, SND900) with mouse and human stem cell derived motor neurons
Tags: human, motor neurons, mouse, protocol, SND150, SND450, SND900, stem cells

Barber, A.C., Evans, R.S., Nieuwenhuis, B., Pearson, C.S., Fuchs, J., MacQueen, A.R., Erp, S.v., Haenzi, B., Hulshof, L.A., Osborne, A., Conceicao, R., Deshpande, S.S., Cave, J., ffrench-Constant, C., Smith, P.D., Okkenhaug, K., Eickholt, B.J., Martin, K.R., Fawcett, J.W., Eva, R., 2019. PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS. bioRxiv, 787994. * uses Xona’s Silicone Devices (SND150) with rat DRG neurons
Tags: DRG, rat, SND150

Gruner, H.N., Bae, B., Lynch, M., Oliver, D., So, K., Mastick, G.S., Yan, W., Miura, P., 2019. Precise removal of Calm1 long 3′ UTR isoform by CRISPR-Cas9 genome editing impairs dorsal root ganglion development in mice. bioRxiv, 553990. * uses Xona’s Silicone Devices (SND450) with mouse DRG neurons
Tags: DRG, mouse, SND450

Teotia, P., Van Hook, M.J., Fischer, D., Ahmad, I., 2019. Human retinal ganglion cell axon regeneration by recapitulating developmental mechanisms: effects of recruitment of the mTOR pathway. Development 146, dev178012. * uses Xona’s Silicone Devices (SND450) with human retinal ganglion cells
Tags: human, retinal ganglion cells, SND450

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