Samar, A., P. Melanie, N. Masahiro, S. Siyuan, C. Tania, L. W. Jeffrey and A. Liliana, 2023. Exosomes promote axon outgrowth and a polarized neuronal morphology by engaging the Wnt-Planar Cell Polarity pathway. bioRxiv: 2023.2010.2028.564542. https://doi.org/10.1101/2023.10.28.564542
Tags: cortical neurons, exosomes, preprint, primary, XC150

Paraskevi, T., S. Jolien, S. Wendy, S. Adria, D. Katarina Stoklund, C. Adriana Margarida Barbosa, P. Arun, H. Andreas, D. Philip Van, M. Thomas and B. Ludo Van Den, 2023. PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. bioRxiv: 2023.2008.2028.555106. https://doi.org/10.1101/2023.08.28.555106
Tags: hiPSC-derived motor neurons, myoblasts, neuromuscular junction (NMJ), preprint, XC150

Costamagna, D., V. Bastianini, M. Corvelyn, R. Duelen, J. Deschrevel, N. De Beukelaer, H. De Houwer, M. Sampaolesi, G. Gayan-Ramirez, A. V. Campenhout and K. Desloovere, 2023. Botulinum Toxin Treatment of Adult Muscle Stem Cells from Children with Cerebral Palsy and hiPSC-Derived Neuromuscular Junctions. Cells 12 DOI: 10.3390/cells12162072. https://doi.org/10.3390/cells12162072
Tags: hiPSC-derived, lower motor neurons, myoblasts, neuromuscular junction (NMJ), XC150

Van Breedam, E., T. Buyle-Huybrecht, J. Govaerts, P. Meysman, A. Bours, M. Boeren, J. Di Stefano, T. Caers, H. De Reu, L. Dirkx, J. Schippers, E. Bartholomeus, M. Lebrun, C. Sadzot-Delvaux, P. Rybakowska, M. E. Alarcón-Riquelme, C. Marañón, K. Laukens, P. Delputte, B. Ogunjimi and P. Ponsaerts, 2023. Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model. Frontiers in Immunology 14. https://doi.org/10.3389/fimmu.2023.1177245
Tags: co-cultures, hiPSC-derived, macrophages, XC150

Gatti, M., K. S. Dittlau, F. Beretti, L. Yedigaryan, M. Zavatti, P. Cortelli, C. Palumbo, E. Bertucci, L. Van Den Bosch, M. Sampaolesi and T. Maraldi, 2023. Human Neuromuscular Junction on a Chip: Impact of Amniotic Fluid Stem Cell Extracellular Vesicles on Muscle Atrophy and NMJ Integrity. International Journal of Molecular Sciences 24(5): 4944. * uses XC150 XonaChips with human-derived myotube and motor neuron co-cultures. https://doi.org/10.3390/ijms24054944
Tags: co-culture, hiPSC-derived motor neurons, human, motor neurons, myotubes, stem cells, XC150

Cai, X., M. Han, F. Lou, Y. Sun, Q. Yin, L. Sun, Z. Wang, X. Li, H. Zhou, Z. Xu, H. Wang, S. Deng, X. Zheng, T. Zhang, Q. Li, B. Zhou and H. Wang, 2023. Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis. Nature Communications 14(1): 2004. * uses XonaChips (XC150) with mouse DRG co-cultures. https://doi.org/10.1038/s41467-023-37798-x
Tags: co-culture, DRG, mouse, primary, XC150

Stoklund Dittlau, K., Terrie, L., Baatsen, P., Kerstens, A., De Swert, L., Janky, R.s., Corthout, N., Masrori, P., Van Damme, P., Hyttel, P., Meyer, M., Thorrez, L., Freude, K., Van Den Bosch, L., 2023. FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms. Molecular Neurodegeneration 18, 5. * uses XonaChips® (XC150) with co-culture of hiPSC-derived motor neurons and astrocytes with human primary myoblasts. https://doi.org/10.1186/s13024-022-00591-3
Tags: astrocytes, co-culture, hiPSC-derived motor neurons, myoblasts, XC150

Antoniou, A., Auderset, L., Kaurani, L., Sebastian, E., Zeng, Y., Allahham, M., Cases-Cunillera, S., Schoch, S., Gründemann, J., Fischer, A., Schneider, A., 2023. Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF. Cell Reports 42 * uses XonaChips® (XC150) and Silicone Devices (TCND500) with mouse cortical and hippocampal neurons (E16). https://doi.org/10.1016/j.celrep.2023.112063
Tags: cortical neurons, hippocampal neurons, mouse, TCND500, XC150

Antoniou, A., Auderset, L., Kaurani, L., Sebastian, E., Zeng, Y., Allahham, M., Cases-Cunillera, S., Schoch, S., Gründemann, J., Fischer, A., Schneider, A., 2023. Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream...

Lotlikar, M.S., Tarantino, M.B., Jorfi, M., Kovacs, D.M., Tanzi, R.E., Bhattacharyya, R., 2022. Microfluidic separation of axonal and somal compartments of neural progenitor cells differentiated in a 3D matrix. STAR Protocols 3, 101028. * uses XonaChips® (XC150, XC450) with human NPCs cultured in 3D using Matrigel® **PROTOCOL** https://doi.org/10.1016/j.xpro.2021.101028
Tags: 3D, human, Matrigel, NPC, protocol, XC150, XC450

Costamagna, D., Casters, V., Beltrà, M., Sampaolesi, M., Van Campenhout, A., Ortibus, E., Desloovere, K., Duelen, R., 2022. Autologous iPSC-Derived Human Neuromuscular Junction to Model the Pathophysiology of Hereditary Spastic Paraplegia, Cells. * uses XonaChips® (XC150) with human iPSC-differentiated lower motor neurons and myoblasts to create in vitro NMJs. https://doi.org/10.3390/cells11213351
Tags: hereditary spastic paraplegia, hiPSC-derived motor neurons, lower motor neurons, myoblasts, neuromuscular junction (NMJ), XC150

Pourshafie, N., Masati, E., Lopez, A., Bunker, E., Snyder, A., Edwards, N.A., Winkelsas, A.M., Fischbeck, K.H., Grunseich, C., 2022. Altered SYNJ2BP-mediated mitochondrial-ER contacts in motor neuron disease. Neurobiol Dis 172, 105832. * uses XonaChips® (XC150) with human iPSC-differentiated motor neurons. https://doi.org/10.1016/j.nbd.2022.105832
Tags: hiPSC-derived motor neurons, human, motor neuron disease, XC150

Bhattacharyya, R., Black, S.E., Lotlikar, M.S., Fenn, R.H., Jorfi, M., Kovacs, D.M., Tanzi, R.E., 2021. Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes. Cell Rep 35, 109134. * uses XonaChips® (XC150, XC450) with human NPCs cultured in 3D using Matrigel® https://doi.org/10.1016/j.celrep.2021.109134
Tags: 3D, human, Matrigel, NPC, XC150, XC450

Stoklund Dittlau, K., Krasnow, E.N., Fumagalli, L., Vandoorne, T., Baatsen, P., Kerstens, A., Giacomazzi, G., Pavie, B., Rossaert, E., Beckers, J., Sampaolesi, M., Van Damme, P., Van Den Bosch, L., 2021. Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition. Stem Cell Reports 16, 2213-2227. * uses XonaChips® (XC150) and Xona’s Silicone Devices (SND75) with human iPSC-differentiated motor neurons and human mesoangioblasts (MAB)-derived myotubes to create in vitro NMJs.

https://doi.org/10.1016/j.stemcr.2021.03.029 
Tags: hiPSC-derived motor neurons, human, neuromuscular junction (NMJ), SND75, XC150

Stoklund Dittlau, K., Krasnow, E.N., Fumagalli, L., Vandoorne, T., Baatsen, P., Kerstens, A., Giacomazzi, G., Pavie, B., Rossaert, E., Beckers, J., Sampaolesi, M., Van Damme, P., Van Den Bosch, L., 2021. Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices. JoVE, e62959. * uses XonaChips® (XC150) and Xona’s Silicone Devices (SND75) with human iPSC-differentiated motor neurons and human mesoangioblasts (MAB)-derived myotubes to create in vitro NMJs. http://doi.org/10.3791/62959
Tags: hiPSC-derived motor neurons, human, motor neurons, neuromuscular junction (NMJ), SND75, XC150

Paranjape, S. R., Nagendran, T., Poole, V., Harris, J., Taylor, A. M. (2019). Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips J. Vis. Exp. (147), e59250, doi:10.3791/59250 (2019). * uses XonaChips® (XC150, XC450, XC900) with human stem cell derived glutamatergic neurons **authored by Xona scientists  https://www.jove.com/video/59250/compartmentalization-human-stem-cell-derived-neurons-within-pre?status=a61256k
Tags: glutamatergic, hiPSC-derived, human, protocol, XC150, XC450, XC900, Xona author

Desforges, M., Le Coupanec, A., Dubeau, P., Bourgouin, A., Lajoie, L., Dubé, M., & Talbot, P. J. (2019). Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?. Viruses12(1), 14. https://doi.org/10.3390/v12010014 * uses XonaChips® (XC150) with murine mixed neurons  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020001/
Tags: cortical neurons, mouse, rat, XC150

Nagendran, T., V. Poole, J. Harris and A. M. Taylor, 2018. Use of Pre-Assembled Plastic Microfluidic Chips for Compartmentalizing Primary Murine Neurons. Journal of visualized experiments : JoVE(141). * uses XC150, XC450, XC900 XonaChips with rat hippocampal neurons.  https://dx.doi.org/10.3791/58421
Tags: hippocampal neurons, mouse, protocol, rat, XC150, XC450, XC900, Xona author

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