Kandhavivorn, W., H. Glaß, T. Herrmannsdörfer, T. M. Böckers, M. Uhlarz, J. Gronemann, R. H. W. Funk, J. Pietzsch, A. Pal and A. Hermann, 2023. Restoring Axonal Organelle Motility and Regeneration in Cultured FUS-ALS Motoneurons through Magnetic Field Stimulation Suggests an Alternative Therapeutic Approach. Cells 12 DOI: 10.3390/cells12111502. * uses Xona's silicone devices (RD900) with hiPSC-derived motor neurons. https://doi.org/10.3390/cells12111502
Tags: hiPSC-derived motor neurons, RD900
Zimyanin, V. L., A.-M. Pielka, H. Glaß, J. Japtok, D. Großmann, M. Martin, A. Deussen, B. Szewczyk, C. Deppmann, E. Zunder, P. M. Andersen, T. M. Boeckers, J. Sterneckert, S. Redemann, A. Storch and A. Hermann, 2023. Live Cell Imaging of ATP Levels Reveals Metabolic Compartmentalization within Motoneurons and Early Metabolic Changes in FUS ALS Motoneurons. Cells 12 DOI: 10.3390/cells12101352. * uses Xona's silicone devices (RD900) with human iPSC-derived motoneurons. https://doi.org/10.3390/cells12101352
Tags: hiPSC-derived motor neurons, human, RD900
Marrone, L., Marchi, P.M., Webster, C.P., Marroccella, R., Coldicott, I., Reynolds, S., Alves-Cruzeiro, J., Yang, Z.-L., Higginbottom, A., Khundadze, M., Shaw, P.J., Hübner, C.A., Livesey, M.R., Azzouz, M., 2022. SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction. Human Molecular Genetics 31, 2693-2710. * uses Xona’s Silicone Devices (RD900) with mouse cortical neurons. https://doi.org/10.1093/hmg/ddac063
Tags: cortical neurons, mouse, RD900
Günther, R., Pal, A., Williams, C., Zimyanin, V.L., Liehr, M., von Neubeck, C., Krause, M., Parab, M.G., Petri, S., Kalmbach, N., Marklund, S.L., Sterneckert, J., Munch Andersen, P., Wegner, F., Gilthorpe, J.D., Hermann, A., 2022. Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS, Cells. * uses Xona’s Silicone Devices (RD900) with hiPSC-derived motor neurons. https://doi.org/10.3390/cells11071246
Tags: ALS, hiPSC-derived motor neurons, RD900
Kulkarni, V.V., Stempel, M.H., Anand, A., Sidibe, D.K., Maday, S., 2022. Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons. The Journal of Neuroscience 42, 8524. https://doi.org/10.1523/JNEUROSCI.1292-22.2022
Tags: astrocytes, co-culture, cortical neurons, mouse, RD900
Pal, A., Kretner, B., Abo-Rady, M., Glaβ, H., Dash, B.P., Naumann, M., Japtok, J., Kreiter, N., Dhingra, A., Heutink, P., Böckers, T.M., Günther, R., Sterneckert, J., Hermann, A., 2021. Concomitant gain and loss of function pathomechanisms in C9ORF72 amyotrophic lateral sclerosis. Life Science Alliance 4, e202000764. * uses Xona’s Silicone Devices (RD900) with human iPSC-differentiated motor neurons
http://doi.org/10.26508/lsa.202000764
Tags: hiPSC-derived motor neurons, human, RD900
Naumann, M., Pal, A., Goswami, A., Lojewski, X., Japtok, J., Vehlow, A., Naujock, M., Günther, R., Jin, M., Stanslowsky, N., Reinhardt, P., Sterneckert, J., Frickenhaus, M., Pan-Montojo, F., Storkebaum, E., Poser, I., Freischmidt, A., Weishaupt, J.H., Holzmann, K., Troost, D., Ludolph, A.C., Boeckers, T.M., Liebau, S., Petri, S., Cordes, N., Hyman, A.A., Wegner, F., Grill, S.W., Weis, J., Storch, A., Hermann, A., 2018. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. Nature Communications 9, 335. * uses Xona’s Silicone Devices (RD900) with human iPSC-differentiated motor neurons https://doi.org/10.1038/s41467-017-02299-1
Tags: hiPSC-derived motor neurons, human, RD900