Ricci, C., M. J. Midroit, F. Caicci, T. Achsel, N. Domínguez-Iturza and C. Bagni (2025). "CYFIP1 governs the development of cortical axons by modulating calcium availability." Nature Communications 16(1): 10764. https://doi.org/10.1038/s41467-025-65801-0
Tags: cortical neurons, mouse, primary, SND450
Qin, T., Y. Jin, Y. Qin, F. Yuan, H. Lu, J. Hu, Y. Cao and C. Li (2025). "Enhancing m6A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury." Neural Regeneration Research 20(6). https://journals.lww.com/nrronline/toc/2025/06000
Tags: primary, SND450
Taguchi, K., Y. Watanabe and M. Tanaka (2025). "SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation." iScience 28(2). https://doi.org/10.1016/j.isci.2025.111935
Tags: primary, TCND500
Wang, W., M. M. Hassan, N. Kapoor-Kaushik, L. Livni, B. Musrie, J. Tang, Z. Mahmud, S. Lai, P. R. Wich, V. Ananthanarayanan, G. Moalem-Taylor and G. Mao (2024). "Neural Tracing Protein-Functionalized Nanoparticles Capable of Fast Retrograde Axonal Transport in Live Neurons." Small 20(39): 2311921. https://doi.org/10.1002/smll.202311921
Tags: DRG, primary, sensory neurons, XC150
Cardanho-Ramos, C., R. A. Simões, Y.-Z. Wang, A. Faria-Pereira, E. Bomba-Warczak, K. Craessaerts, M. Spinazzi, J. N. Savas and V. A. Morais (2024). "Local mitochondrial replication in the periphery of neurons requires the eEF1A1 protein and the translation of nuclear-encoded proteins." iScience 27(4). https://doi.org/10.1016/j.isci.2024.109136
Tags: mouse, primary, SND450
Pisciottani, A., L. Croci, F. Lauria, C. Marullo, E. Savino, A. Ambrosi, P. Podini, M. Marchioretto, F. Casoni, O. Cremona, S. Taverna, A. Quattrini, J.-M. Cioni, G. Viero, F. Codazzi and G. G. Consalez, 2023. Neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis. Frontiers in Cellular Neuroscience 17. https://doi.org/10.3389/fncel.2023.1253543
Tags: cortical neurons, mouse, primary, SND450
Kropf, E., A. Shekari, S. Jaberi, A. Puri, C. Wu and M. Fahnestock, 2023. Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75(NTR). Front Mol Neurosci 16: 1241420. https://doi.org/10.3389%2Ffnmol.2023.1241420
Tags: basal forebrain cholinergic neurons, primary, XC450
Samar, A., P. Melanie, N. Masahiro, S. Siyuan, C. Tania, L. W. Jeffrey and A. Liliana, 2023. Exosomes promote axon outgrowth and a polarized neuronal morphology by engaging the Wnt-Planar Cell Polarity pathway. bioRxiv: 2023.2010.2028.564542. https://doi.org/10.1101/2023.10.28.564542
Tags: cortical neurons, exosomes, preprint, primary, XC150
Abdolhossein, Z., S. Saeede, B. Michael and S. Michael, 2023. Prevention of tau accumulation through inhibition of hnRNP R-dependent axonal <em>Mapt</em> mRNA localization. bioRxiv: 2023.2007.2019.549639. https://doi.org/10.1101/2023.07.19.549639
Tags: motor neurons, mouse, preprint, primary, SND150
Moya-Alvarado, G., A. Aguirre-Soto and F. C. Bronfman, 2024. Multiple Labeling of Compartmentalized Cortical Neurons in Microfluidic Chambers. Bio Protoc 14(1): e4911. 10.21769/BioProtoc.4911
Tags: primary, RD450, SND450
Chen, C., R. Kumbhar, H. Wang, X. Yang, K. Gadhave, C. Rastegar, Y. Kimura, A. Behensky, S. Katakam, D. Jeong, L. Wang, A. Wang, R. Chen, S. Zhang, L. Jin, C. J. Workman, D. A. A. Vignali, O. Pletinkova, D. W. Nauen, P. C. Wong, J. C. Troncoso, M. Ying, V. L. Dawson, T. M. Dawson and X. Mao, 2023. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. bioRxiv. 10.1101/2023.05.16.541015
Tags: mouse, preprint, primary, TCND1000
Danastas, K., G. Guo, J. Merjane, N. Hong, A. Larsen, M. Miranda-Saksena and L. Cunningham Anthony, 2023. Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons. mBio 14(5): e01818-01823. https://doi.org/10.1128/mbio.01818-23
Tags: primary, rat, SND450, viral infection
Mutschler, C., S. V. Fazal, N. Schumacher, A. Loreto, M. P. Coleman and P. Arthur-Farraj, 2023. Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann cell–neuron cocultures. Journal of Cell Science 136(18): jcs261557. * uses Xona's silicone devices (SND150) with mouse primary co-cultures of DRG and myelinating Schwann cells. https://doi.org/10.1242/jcs.261557
Tags: co-culture, DRG, mouse, myelination, primary, Schwann cells, SND150
Wu, Z., R. Zhu, Y. Yu, J. Wang, X. Hu, W. Xu, Y. Ren, C. Li, Z. Zeng, B. Ma, N. Xie, G. Lin, B. Ma, R. Zhu, K. Ye and L. Cheng, 2023. Spinal cord injury-activated C/EBPβ-AEP axis mediates cognitive impairment through APP C586/Tau N368 fragments spreading. Progress in Neurobiology 227: 102467. https://doi.org/10.1016/j.pneurobio.2023.102467
Tags: hippocampal neurons, primary, SND450
Brummer, T., M. Schillner, F. Steffen, F. Kneilmann, B. Wasser, T. Uphaus, F. Zipp and S. Bittner, 2023. Spatial transcriptomics and neurofilament light chain reveal changes in lesion patterns in murine autoimmune neuroinflammation. Journal of Neuroinflammation 20(1): 262. * uses XC450 XonaChips with microglia-axon co-cultures. https://doi.org/10.1186/s12974-023-02947-y
Tags: cortical neurons, microglia, primary, XC450
Salehi, S., A. Zare, G. Prezza, J. Bader, C. Schneider, U. Fischer, F. Meissner, M. Mann, M. Briese and M. Sendtner, 2023. Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr. Nature Communications 14(1): 4158. * uses IND150 and RD150 silicone devices with mouse motoneurons. https://doi.org/10.1038/s41467-023-39787-6
Tags: IND150, motor neurons, mouse, primary, RD450
Siddiq, M. M., C. A. Toro, N. P. Johnson, J. Hansen, Y. Xiong, W. Mellado, R. E. Tolentino, K. Johnson, G. Jayaraman, Z. Suhail, L. Harlow, J. Dai, K. G. Beaumont, R. Sebra, D. E. Willis, C. P. Cardozo and R. Iyengar, 2023. Spinal cord injury regulates circular RNA expression in axons. Front Mol Neurosci 16: 1183315. * uses Xona's silicone devices (SND450) with primary cortical neurons https://doi.org/10.3389%2Ffnmol.2023.1183315
Tags: cortical neurons, injury, mouse, primary, rat, SND450
Chan, C., K. Ramhari, W. Hu, Y. Xiuli, G. Kundlik, R. Cyrus, K. Yasuyoshi, B. Adam, K. Sruthi, J. Deok, W. Liang, W. Anthony, C. Rong, Z. Shu, J. Lingtao, J. W. Creg, A. A. V. Dario, P. Olga, W. N. David, C. W. Philip, C. T. Juan, Y. Mingyao, L. D. Valina, M. D. Ted and M. Xiaobo, 2023. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. bioRxiv: 2023.2005.2016.541015. * uses Xona's silicone devices (TCND1000) with primary mouse cortical neurons. https://doi.org/10.1101/2023.05.16.541015
Tags: cortical neurons, mouse, preprint, primary, TCND1000
Clara, M., V. F. Shaline, S. Nathalie, L. Andrea, P. C. Michael and A.-F. Peter, 2023. Distinct axo-protective and axo-destructive roles for Schwann cells after injury in a novel compartmentalised mouse myelinating coculture system. bioRxiv: 2023.2005.2019.541371. * uses Xona's silicone devices (SND150) with mouse primary co-cultures of DRG and myelinating Schwann cells. https://doi.org/10.1101/2023.05.19.541371
Tags: co-culture, DRG, mouse, myelination, preprint, primary, Schwann cells, SND150
Alessandra, P., C. Laura, L. Fabio, M. Chiara, S. Elisa, A. Alessandro, P. Paola, M. Marta, C. Filippo, C. Ottavio, T. Stefano, Q. Angelo, C. Jean-Michel, V. Gabriella, C. Franca and G. G. Consalez, 2023. Two neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis. bioRxiv: 2023.2005.2017.540919. * uses Xona's silicone devices (SND450) with mouse cortical neurons. https://doi.org/10.1101/2023.05.17.540919
Tags: cortical neurons, mouse, preprint, primary, SND450
Cai, X., M. Han, F. Lou, Y. Sun, Q. Yin, L. Sun, Z. Wang, X. Li, H. Zhou, Z. Xu, H. Wang, S. Deng, X. Zheng, T. Zhang, Q. Li, B. Zhou and H. Wang, 2023. Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis. Nature Communications 14(1): 2004. * uses XonaChips (XC150) with mouse DRG co-cultures. https://doi.org/10.1038/s41467-023-37798-x
Tags: co-culture, DRG, mouse, primary, XC150
Salas-Lucia, F., C. Fekete, R. Sinkó, P. Egri, K. Rada, Y. Ruska, B. Gereben and A. C. Bianco, 2023. Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain. eLife 12: e82683. * uses XonaChips (XC450) with primary mouse cortical neurons. https://doi.org/10.7554/eLife.82683
Tags: cortical neurons, mouse, primary, XC450
Kaniyappan, S., Balaji, V., Wang, Y., Mandelkow, E., 2023. Microfluidic Chamber Technology to Study Missorting and Spreading of Tau Protein in Alzheimer’s Disease, in: Cieplak, A.S. (Ed.), Protein Aggregation: Methods and Protocols. New York, NY: Springer US, pp. 111-123. * uses Xona’s Silicone (PDMS) Devices (RD150, TCND1000) with primary rat cortical or hippocampal neurons **PROTOCOL** https://doi.org/10.1007/978-1-0716-2597-2_9
Tags: cortical neurons, hippocampal neurons, primary, protocol, rat, RD150, TCND1000
Yang, X., Tohda, C., 2023. Axonal Regeneration Mediated by a Novel Axonal Guidance Pair, Galectin-1 and Secernin-1. Mol Neurobiol 60, 1250-1266. https://doi.org/10.1007/s12035-022-03125-6
Tags: hippocampal neurons, primary
Hennlein, L., Ghanawi, H., Gerstner, F., Palominos García, E., Yildirim, E., Saal-Bauernschubert, L., Moradi, M., Deng, C., Klein, T., Appenzeller, S., Sauer, M., Briese, M., Simon, C., Sendtner, M., Jablonka, S., 2023. Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy. Journal of Cell Biology 222, e202204113. https://doi.org/10.1083/jcb.202204113
Tags: motor neurons, mouse, primary, SND150, spinal muscular atrophy
Arsić, A., Nikić-Spiegel, I., 2022. The tail domain of neurofilament light chain accumulates in neuronal nuclei during oxidative injury. bioRxiv, 2022.2003.2003.481279. * uses Xona’s Silicone Devices (SND450) with primary mouse cortical neurons. https://doi.org/10.1101/2022.03.03.481279
Tags: cortical neurons, mouse, preprint, primary, SND450
Rodriguez, C.M., Bechek, S.C., Jones, G.L., Nakayama, L., Akiyama, T., Kim, G., Solow-Cordero, D.E., Strittmatter, S.M., Gitler, A.D., 2022. Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2. Cell Rep 41, 111505. * uses XonaChips® (XC450) with primary mouse cortical neurons https://doi.org/10.1016/j.celrep.2022.111505
Tags: cortical neurons, mouse, primary, XC450
Hansen, J., Siddiq, M.M., Yadaw, A.S., Tolentino, R.E., Rabinovich, V., Jayaraman, G., Jain, M.R., Liu, T., Li, H., Xiong, Y., Goldfarb, J., Iyengar, R., 2022. Whole cell response to receptor stimulation involves many deep and distributed subcellular biochemical processes. Journal of Biological Chemistry 298. * uses Xona’s Silicone Devices (SND150) with primary rat cortical neurons. https://doi.org/10.1016/j.jbc.2022.102325
Tags: cortical neurons, primary, rat, SND150
Hofmann, M., Biller, L., Michel, U., Bähr, M., Koch, J.C., 2022. Cytoskeletal assembly in axonal outgrowth and regeneration analyzed on the nanoscale. Sci Rep 12, 14387. * uses Xona’s Silicone Devices (SND450) with primary rat cortical neurons. https://doi.org/10.1038/s41598-022-18562-5
Tags: cortical neurons, primary, rat, SND450
Westergard, T., Jensen, Brigid K., Wen, X., Cai, J., Kropf, E., Iacovitti, L., Pasinelli, P., Trotti, D., 2016. Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD. Cell Reports 17, 645-652. * uses Xona’s Silicone (PDMS) Devices (SND150) with primary rat cortical neurons https://doi.org/10.1016/j.celrep.2016.09.032
Tags: cortical neurons, primary, rat, SND150
Taylor, A. M., D. C. Dieterich, H. T. Ito, S. A. Kim and E. M. Schuman, 2010. Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron 66(1): 57-68. https://doi.org/10.1016/j.neuron.2010.03.022
Tags: hippocampal neurons, microfluidic local perfusion device, primary, rat, SND150, SND450, SND900, uLP, Xona author