Salehi, S., A. Zare, G. Prezza, J. Bader, C. Schneider, U. Fischer, F. Meissner, M. Mann, M. Briese and M. Sendtner, 2023. Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr. Nature Communications 14(1): 4158. * uses IND150 and RD150 silicone devices with mouse motoneurons. https://doi.org/10.1038/s41467-023-39787-6
Tags: IND150, motor neurons, mouse, primary, RD450
Gatti, M., K. S. Dittlau, F. Beretti, L. Yedigaryan, M. Zavatti, P. Cortelli, C. Palumbo, E. Bertucci, L. Van Den Bosch, M. Sampaolesi and T. Maraldi, 2023. Human Neuromuscular Junction on a Chip: Impact of Amniotic Fluid Stem Cell Extracellular Vesicles on Muscle Atrophy and NMJ Integrity. International Journal of Molecular Sciences 24(5): 4944. * uses XC150 XonaChips with human-derived myotube and motor neuron co-cultures. https://doi.org/10.3390/ijms24054944
Tags: co-culture, hiPSC-derived motor neurons, human, motor neurons, myotubes, stem cells, XC150
Hennlein, L., Ghanawi, H., Gerstner, F., Palominos García, E., Yildirim, E., Saal-Bauernschubert, L., Moradi, M., Deng, C., Klein, T., Appenzeller, S., Sauer, M., Briese, M., Simon, C., Sendtner, M., Jablonka, S., 2023. Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy. Journal of Cell Biology 222, e202204113. https://doi.org/10.1083/jcb.202204113
Tags: motor neurons, mouse, primary, SND150, spinal muscular atrophy
Hao, J., Wells, M.F., Niu, G., San Juan, I.G., Limone, F., Fukuda, A., Leyton-Jaimes, M.F., Joseph, B., Qian, M., Mordes, D.A., Budnik, B., Dou, Z., Eggan, K., 2021. Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons. bioRxiv, 2021.2010.2011.464011. https://doi.org/10.1101/2021.10.11.464011
Tags: human, motor neurons, preprint, SND150
Güner, F., Pozner, T., Krach, F., Prots, I., Loskarn, S., Schlötzer-Schrehardt, U., Winkler, J., Winner, B., Regensburger, M., 2021. Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons. Frontiers in Neuroscience 15. * uses Xona’s Silicone Devices (SND450) with human iPSC-differentiated motor neuron progenitors and human cerebellar astrocytes co-cultures. https://doi.org/10.3389/fnins.2021.680572
Tags: astrocytes, co-culture, hiPSC-derived, hiPSC-derived motor neurons, human, motor neurons, SND450
Stoklund Dittlau, K., Krasnow, E.N., Fumagalli, L., Vandoorne, T., Baatsen, P., Kerstens, A., Giacomazzi, G., Pavie, B., Rossaert, E., Beckers, J., Sampaolesi, M., Van Damme, P., Van Den Bosch, L., 2021. Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices. JoVE, e62959. * uses XonaChips® (XC150) and Xona’s Silicone Devices (SND75) with human iPSC-differentiated motor neurons and human mesoangioblasts (MAB)-derived myotubes to create in vitro NMJs. http://doi.org/10.3791/62959
Tags: hiPSC-derived motor neurons, human, motor neurons, neuromuscular junction (NMJ), SND75, XC150
Klim, J.R., Williams, L.A., Limone, F., Guerra San Juan, I., Davis-Dusenbery, B.N., Mordes, D.A., Burberry, A., Steinbaugh, M.J., Gamage, K.K., Kirchner, R., Moccia, R., Cassel, S.H., Chen, K., Wainger, B.J., Woolf, C.J., Eggan, K., 2019. ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nat Neurosci. Feb;22(2):167-179. doi: 10.1038/s41593-018-0300-4. * uses Xona’s Silicone Devices (SND150) with human stem cell (iPSC and ESC) derived motor neurons https://www.ncbi.nlm.nih.gov/pubmed/30643292
Tags: human, motor neurons, SND150, stem cells
Nijssen, J., Aguila, J. and Hedlund, E. (2019). Axon-seq for in Depth Analysis of the RNA Content of Neuronal Processes. Bio-protocol 9(14): e3312. DOI: 10.21769/BioProtoc.3312. * uses Xona’s Silicone Devices (SND150, SND450, SND900) with mouse and human stem cell derived motor neurons https://bio-protocol.org/e3312
Tags: human, motor neurons, mouse, protocol, SND150, SND450, SND900, stem cells
Nijssen, J., Aguila, J., Hoogstraaten, R., Kee, N., Hedlund, E., 2018. Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS. Stem Cell Reports 11, 1565-1578. * uses SND150 silicone devices with human motor neurons. https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(18)30473-9
Tags: ALS, human, motor neurons, SND150