Higerd-Rusli, G.P., Tyagi, S., Baker, C.A., Liu, S., Dib-Hajj, F.B., Dib-Hajj, S.D., Waxman, S.G., 2023. Inflammation differentially controls transport of depolarizing Nav versus hyperpolarizing Kv channels to drive rat nociceptor activity. Proceedings of the National Academy of Sciences 120, e2215417120. https://www.pnas.org/doi/10.1073/pnas.2215417120
Tags: basic research, DOC450, postnatal, rat
Higerd-Rusli, G.P., Tyagi, S., Liu, S., Dib-Hajj, F.B., Waxman, S.G., Dib-Hajj, S.D., 2023. The fates of internalized NaV1.7 channels in sensory neurons: Retrograde cotransport with other ion channels, axon-specific recycling, and degradation. Journal of Biological Chemistry 299 * uses Xona’s Silicone Devices (DOC450) with primary rat DRGs (P2-4). https://doi.org/10.1016/j.jbc.2022.102816
Tags: basic research, DOC450, postnatal, rat
Higerd-Rusli, G.P., Alsaloum, M., Tyagi, S., Sarveswaran, N., Estacion, M., Akin, E.J., Dib-Hajj, F.B., Liu, S., Sosniak, D., Zhao, P., Dib-Hajj, S.D., Waxman, S.G., 2022. Depolarizing NaV and Hyperpolarizing KV Channels Are Co-Trafficked in Sensory Neurons. The Journal of Neuroscience 42, 4794.
https://doi.org/10.1523/JNEUROSCI.0058-22.2022
Tags: DOC450, postnatal, rat, sensory neurons
Akin, E.J., Alsaloum, M., Higerd, G.P., Liu, S., Zhao, P., Dib-Hajj, F.B., Waxman, S.G., Dib-Hajj, S.D., 2021. Paclitaxel increases axonal localization and vesicular trafficking of Nav1.7. Brain. * uses Xona’s Silicone Devices (DOC450) with rat DRG neurons https://doi.org/10.1093/brain/awab113
Tags: DOC450, DRG, rat
Kamande, J.W., Nagendran, T., Harris, J., Taylor, A.M., 2019. Multi-compartment Microfluidic Device Geometry and Covalently Bound Poly-D-Lysine Influence Neuronal Maturation. Front. Bioeng. Biotechnol. | doi: 10.3389/fbioe.2019.00084. * uses Xona’s Silicone Devices (SND450, DOC450) with human stem cell derived glutamatergic neurons **Original research authored by Xona scientists** https://www.frontiersin.org/articles/10.3389/fbioe.2019.00084/abstract
Tags: DOC450, glutamatergic, hiPSC-derived, human, SND450, Xona author