Pisciottani, A., L. Croci, F. Lauria, C. Marullo, E. Savino, A. Ambrosi, P. Podini, M. Marchioretto, F. Casoni, O. Cremona, S. Taverna, A. Quattrini, J.-M. Cioni, G. Viero, F. Codazzi and G. G. Consalez, 2023. Neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis. Frontiers in Cellular Neuroscience 17. https://doi.org/10.3389/fncel.2023.1253543
Tags: cortical neurons, mouse, primary, SND450

Samar, A., P. Melanie, N. Masahiro, S. Siyuan, C. Tania, L. W. Jeffrey and A. Liliana, 2023. Exosomes promote axon outgrowth and a polarized neuronal morphology by engaging the Wnt-Planar Cell Polarity pathway. bioRxiv: 2023.2010.2028.564542. https://doi.org/10.1101/2023.10.28.564542
Tags: cortical neurons, exosomes, preprint, primary, XC150

Kakuda, K., K. Ikenaka, A. Kuma, J. Doi, C. Aguirre, N. Wang, T. Ajiki, C.-J. Choong, Y. Kimura, S. M. M. Badawy, T. Shima, S. Nakamura, K. Baba, S. Nagano, Y. Nagai, T. Yoshimori and H. Mochizuki, 2024. Lysophagy protects against propagation of α-synuclein aggregation through ruptured lysosomal vesicles. Proceedings of the National Academy of Sciences 121(1): e2312306120. https://doi.org/10.1073/pnas.2312306120
Tags: cortical neurons, mouse, SND450

Brummer, T., M. Schillner, F. Steffen, F. Kneilmann, B. Wasser, T. Uphaus, F. Zipp and S. Bittner, 2023. Spatial transcriptomics and neurofilament light chain reveal changes in lesion patterns in murine autoimmune neuroinflammation. Journal of Neuroinflammation 20(1): 262. * uses XC450 XonaChips with microglia-axon co-cultures.  https://doi.org/10.1186/s12974-023-02947-y
Tags: cortical neurons, microglia, primary, XC450

Siddiq, M. M., C. A. Toro, N. P. Johnson, J. Hansen, Y. Xiong, W. Mellado, R. E. Tolentino, K. Johnson, G. Jayaraman, Z. Suhail, L. Harlow, J. Dai, K. G. Beaumont, R. Sebra, D. E. Willis, C. P. Cardozo and R. Iyengar, 2023. Spinal cord injury regulates circular RNA expression in axons. Front Mol Neurosci 16: 1183315. * uses Xona's silicone devices (SND450) with primary cortical neurons https://doi.org/10.3389%2Ffnmol.2023.1183315
Tags: cortical neurons, injury, mouse, primary, rat, SND450

Chan, C., K. Ramhari, W. Hu, Y. Xiuli, G. Kundlik, R. Cyrus, K. Yasuyoshi, B. Adam, K. Sruthi, J. Deok, W. Liang, W. Anthony, C. Rong, Z. Shu, J. Lingtao, J. W. Creg, A. A. V. Dario, P. Olga, W. N. David, C. W. Philip, C. T. Juan, Y. Mingyao, L. D. Valina, M. D. Ted and M. Xiaobo, 2023. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. bioRxiv: 2023.2005.2016.541015. * uses Xona's silicone devices (TCND1000) with primary mouse cortical neurons.  https://doi.org/10.1101/2023.05.16.541015
Tags: cortical neurons, mouse, preprint, primary, TCND1000

Alessandra, P., C. Laura, L. Fabio, M. Chiara, S. Elisa, A. Alessandro, P. Paola, M. Marta, C. Filippo, C. Ottavio, T. Stefano, Q. Angelo, C. Jean-Michel, V. Gabriella, C. Franca and G. G. Consalez, 2023. Two neuronal models of TDP-43 proteinopathy display reduced axonal translation, increased oxidative stress, and defective exocytosis. bioRxiv: 2023.2005.2017.540919. * uses Xona's silicone devices (SND450) with mouse cortical neurons.  https://doi.org/10.1101/2023.05.17.540919
Tags: cortical neurons, mouse, preprint, primary, SND450

Salas-Lucia, F., C. Fekete, R. Sinkó, P. Egri, K. Rada, Y. Ruska, B. Gereben and A. C. Bianco, 2023. Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain. eLife 12: e82683. * uses XonaChips (XC450) with primary mouse cortical neurons. https://doi.org/10.7554/eLife.82683
Tags: cortical neurons, mouse, primary, XC450

Neel DV, Basu H, Gunner G, Bergstresser MD, Giadone RM, Chung H, Miao R, Chou V, Brody E, Jiang X, Lee E, Watts ME, Marques C, Held A, Wainger B, Lagier-Tourenne C, Zhang YJ, Petrucelli L, Young-Pearse TL, Chen-Plotkin AS, Rubin LL, Lieberman J, Chiu IM. Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration. Neuron. 2023 Apr 19;111(8):1222-1240.e9. * uses XonaChips® (XC450) and Xona’s Silicone Devices (RD450) using mouse cortical neurons. http://doi.org/10.1016/j.neuron.2023.02.019
Tags: cortical neurons, mouse, RD450, XC450

Kaniyappan, S., Balaji, V., Wang, Y., Mandelkow, E., 2023. Microfluidic Chamber Technology to Study Missorting and Spreading of Tau Protein in Alzheimer’s Disease, in: Cieplak, A.S. (Ed.), Protein Aggregation: Methods and Protocols. New York, NY: Springer US, pp. 111-123. * uses Xona’s Silicone (PDMS) Devices (RD150, TCND1000) with primary rat cortical or hippocampal neurons **PROTOCOL** https://doi.org/10.1007/978-1-0716-2597-2_9
Tags: cortical neurons, hippocampal neurons, primary, protocol, rat, RD150, TCND1000

Antoniou, A., Auderset, L., Kaurani, L., Sebastian, E., Zeng, Y., Allahham, M., Cases-Cunillera, S., Schoch, S., Gründemann, J., Fischer, A., Schneider, A., 2023. Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF. Cell Reports 42 * uses XonaChips® (XC150) and Silicone Devices (TCND500) with mouse cortical and hippocampal neurons (E16). https://doi.org/10.1016/j.celrep.2023.112063
Tags: cortical neurons, hippocampal neurons, mouse, TCND500, XC150

Antoniou, A., Auderset, L., Kaurani, L., Sebastian, E., Zeng, Y., Allahham, M., Cases-Cunillera, S., Schoch, S., Gründemann, J., Fischer, A., Schneider, A., 2023. Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream...

Arsić, A., Nikić-Spiegel, I., 2022. The tail domain of neurofilament light chain accumulates in neuronal nuclei during oxidative injury. bioRxiv, 2022.2003.2003.481279. * uses Xona’s Silicone Devices (SND450) with primary mouse cortical neurons. https://doi.org/10.1101/2022.03.03.481279
Tags: cortical neurons, mouse, preprint, primary, SND450

Lie Pearl, P.Y., Yoo, L., Goulbourne Chris, N., Berg Martin, J., Stavrides, P., Huo, C., Lee, J.-H., Nixon Ralph, A., Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca2+ efflux and disrupted by PSEN1 loss of function. Science Advances 8, eabj5716. * uses Xona’s Silicone Devices (SND450) with mouse cortical neurons. https://doi.org/10.1126/sciadv.abj5716
Tags: cortical neurons, mouse, SND450

Marrone, L., Marchi, P.M., Webster, C.P., Marroccella, R., Coldicott, I., Reynolds, S., Alves-Cruzeiro, J., Yang, Z.-L., Higginbottom, A., Khundadze, M., Shaw, P.J., Hübner, C.A., Livesey, M.R., Azzouz, M., 2022. SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction. Human Molecular Genetics 31, 2693-2710. * uses Xona’s Silicone Devices (RD900) with mouse cortical neurons. https://doi.org/10.1093/hmg/ddac063
Tags: cortical neurons, mouse, RD900

Marchi, P.M., Marrone, L., Brasseur, L., Coens, A., Webster, C.P., Bousset, L., Destro, M., Smith, E.F., Walther, C.G., Alfred, V., Marroccella, R., Graves, E.J., Robinson, D., Shaw, A.C., Wan, L.M., Grierson, A.J., Ebbens, S.J., De Vos, K.J., Hautbergue, G.M., Ferraiuolo, L., Melki, R., Azzouz, M., 2022. C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life Science Alliance 5, e202101276. * uses Xona’s Silicone Devices (RD450) with mouse cortical neurons. https://doi.org/10.26508/lsa.202101276
Tags: cortical neurons, mouse, RD450

Rodriguez, C.M., Bechek, S.C., Jones, G.L., Nakayama, L., Akiyama, T., Kim, G., Solow-Cordero, D.E., Strittmatter, S.M., Gitler, A.D., 2022. Targeting RTN4/NoGo-Receptor reduces levels of ALS protein ataxin-2. Cell Rep 41, 111505. * uses XonaChips® (XC450) with primary mouse cortical neurons https://doi.org/10.1016/j.celrep.2022.111505
Tags: cortical neurons, mouse, primary, XC450

Hansen, J., Siddiq, M.M., Yadaw, A.S., Tolentino, R.E., Rabinovich, V., Jayaraman, G., Jain, M.R., Liu, T., Li, H., Xiong, Y., Goldfarb, J., Iyengar, R., 2022. Whole cell response to receptor stimulation involves many deep and distributed subcellular biochemical processes. Journal of Biological Chemistry 298. * uses Xona’s Silicone Devices (SND150) with primary rat cortical neurons. https://doi.org/10.1016/j.jbc.2022.102325
Tags: cortical neurons, primary, rat, SND150

Hofmann, M., Biller, L., Michel, U., Bähr, M., Koch, J.C., 2022. Cytoskeletal assembly in axonal outgrowth and regeneration analyzed on the nanoscale. Sci Rep 12, 14387. * uses Xona’s Silicone Devices (SND450) with primary rat cortical neurons. https://doi.org/10.1038/s41598-022-18562-5
Tags: cortical neurons, primary, rat, SND450

Kulkarni, V.V., Stempel, M.H., Anand, A., Sidibe, D.K., Maday, S., 2022. Retrograde Axonal Autophagy and Endocytic Pathways Are Parallel and Separate in Neurons. The Journal of Neuroscience 42, 8524. https://doi.org/10.1523/JNEUROSCI.1292-22.2022
Tags: astrocytes, co-culture, cortical neurons, mouse, RD900

Zhu, B., Liu, Y., Hwang, S., Archuleta, K., Huang, H., Campos, A., Murad, R., Piña-Crespo, J., Xu, H., Huang, T.Y., 2022. Trem2 deletion enhances tau dispersion and pathology through microglia exosomes. Molecular Neurodegeneration 17, 58. * uses Xona’s Silicone (PDMS) Devices (TCND1000) with mouse cortical neurons. https://doi.org/10.1186/s13024-022-00562-8
Tags: cortical neurons, mouse, TCND1000

Brás, I.C., Khani, M.H., Riedel, D., Parfentev, I., Gerhardt, E., van Riesen, C., Urlaub, H., Gollisch, T., Outeiro, T.F., 2022. Ectosomes and exosomes modulate neuronal spontaneous activity. Journal of Proteomics 269, 104721. * uses Xona’s Silicone Devices (TCND1000) with mouse cortical neurons https://doi.org/10.1016/j.jprot.2022.104721
Tags: cortical neurons, mouse, TCND1000

Mao, X., Gu, H., Kim, D., Kimura, Y., Wang, N., Xu, E., Wang, H., Chen, C., Zhang, S., Jia, C., Liu, Y., Bian, H., Karuppagounder, S.S., Jia, L., Ke, X., Chang, M., Li, A., Yang, J., Rastegar, C., Sriparna, M., Ge, P., Brahmachari, S., Kim, S., Zhang, S., Shimoda, Y., Saar, M., Workman, C.J., Vignali, D.A.A., Muller, U.C., Liu, C., Ko, H.S., Dawson, V.L., Dawson, T.M., 2021. Aplp1 and the Aplp1-Lag3 Complex facilitates transmission of pathologic α-synuclein. bioRxiv, 2021.2005.2001.442157. https://doi.org/10.1101/2021.05.01.442157
Tags: cortical neurons, mouse, preprint, TCND1000

Ha, T.-Y., Choi, Y.R., Noh, H.R., Cha, S.-H., Kim, J.-B., Park, S.M., 2021. Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons. Molecular Brain 14, 122. * uses Xona’s Silicone Devices (TCND1000) with mouse cortical neurons and compartmentalized α-syn fibrils https://doi.org/10.1186/s13041-021-00834-2 
Tags: cortical neurons, mouse, TCND1000

Lie, P.P.Y., Yang, D.-S., Stavrides, P., Goulbourne, C.N., Zheng, P., Mohan, P.S., Cataldo, A.M., Nixon, R.A., 2021. Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons. Cell Rep 35, 109034. * uses Xona’s Silicone Devices (RD450) with embryonic mouse cortical neurons. https://doi.org/10.1016/j.celrep.2021.109034
Tags: cortical neurons, embryonic, mouse, RD450

Sundaramoorthy V, Green D, Locke K, O’Brien CM, Dearnley M, et al. (2020) Novel role of SARM1 mediated axonal degeneration in the pathogenesis of rabies. PLOS Pathogens 16(2): e1008343. * uses Xona’s Silicone Devices (SND450) with mouse cortical and DRG neurons https://doi.org/10.1371/journal.ppat.1008343
Tags: cortical neurons, DRG, mouse, SND450

Cristiano Lucci, Raquel Mesquita-Ribeiro, Alex Rathbone, Federico Dajas-Bailador (2020). Spatiotemporal regulation of GSK3β levels by miRNA-26a controls axon development in cortical neurons. Development 147: dev180232 doi: 10.1242/dev.180232 * uses Xona’s Silicone Devices (SND150) with mouse cortical neurons
Tags: cortical neurons, mouse, SND150

Fujita, Y., Nakanishi, T., Ueno, M., Itohara, S., Yamashita, T., 2020. Netrin-G1 Regulates Microglial Accumulation along Axons and Supports the Survival of Layer V Neurons in the Postnatal Mouse Brain. Cell Rep 31, 107580. * uses Xona’s Silicone Devices (SND450) with mouse cortical neurons co-cultured with microglia  https://doi.org/10.1016/j.celrep.2020.107580
Tags: co-culture, cortical neurons, microglia, mouse, SND450

Tian, N., Hanson, K.A., Canty, A.J., Vickers, J.C., King, A.E., 2020. Microtubule-dependent processes precede pathological calcium influx in excitotoxin-induced axon degeneration. J Neurochem 152, 542-555. * uses Xona’s Silicone Devices (SND450) with mouse cortical neurons https://doi.org/10.1111/jnc.14909
Tags: cortical neurons, mouse, SND450

Fujita, Y., Yamashita, T., 2020. Protocol for Co-culture of Microglia with Axons. STAR Protocols, 100111.  * uses Xona’s Silicone Devices (SND450) with mouse co-cultures with cortical neurons and microglia https://doi.org/10.1016/j.xpro.2020.100111
Tags: co-culture, cortical neurons, mouse, SND450

Zhang, Y., Qin, Y., Chopp, M., Li, C., Kemper, A., Liu, X., Wang, X., Zhang, L., Zhang Zheng, G., 2020. Ischemic Cerebral Endothelial Cell–Derived Exosomes Promote Axonal Growth. Stroke 51, 3701-3712. * uses Xona’s Silicone Devices (SND450, TCND500) with rat cortical neurons and exosomes isolated from cerebral endothelial cells (CECs) http://doi.org/10.1161/STROKEAHA.120.031728
Tags: cortical neurons, rat, SND450, TCND500

Li, C., Zhang, Y., Levin, A.M., Fan, B.Y., Teng, H., Ghannam, M.M., Chopp, M., Zhang, Z.G., 2019. Distal Axonal Proteins and Their Related MiRNAs in Cultured Cortical Neurons. Mol Neurobiol. Apr;56(4):2703-2713. doi: 10.1007/s12035-018-1266-7. * uses Xona’s Silicone Devices (SND450) with rat cortical neurons  https://www.ncbi.nlm.nih.gov/pubmed/30054858
Tags: cortical neurons, rat, SND450

Zheng, Y., Zhang, X., Wu, X., Jiang, L., Ahsan, A., Ma, S., Xiao, Z., Han, F., Qin, Z.-H., Hu, W., Chen, Z., 2019. Somatic autophagy of axonal mitochondria in ischemic neurons. The Journal of cell biology 218, 1891-1907. doi: 10.1083/jcb.201804101 * uses Xona’s Silicone Devices (RD450) with mouse cortical neurons  https://www.ncbi.nlm.nih.gov/pubmed/30979799
Tags: cortical neurons, mouse, RD450

Pu, H., Shi, Y., Zhang, L., Lu, Z., Ye, Q., Leak, R.K., Xu, F., Ma, S., Mu, H., Wei, Z., Xu, N., Xia, Y., Hu, X., Hitchens, T.K., Bennett, M.V.L., Chen, J., 2019. Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke. Proceedings of the National Academy of Sciences 116, 9115, doi: 10.1073/pnas.1821979116.* uses Xona’s Silicone Devices (SND450) with rat cortical neurons  https://www.ncbi.nlm.nih.gov/pubmed/30996120
Tags: cortical neurons, rat, SND450

Desforges, M., Le Coupanec, A., Dubeau, P., Bourgouin, A., Lajoie, L., Dubé, M., & Talbot, P. J. (2019). Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?. Viruses12(1), 14. https://doi.org/10.3390/v12010014 * uses XonaChips® (XC150) with murine mixed neurons  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020001/
Tags: cortical neurons, mouse, rat, XC150

Shekari, A. & Fahnestock, M. (2019). Retrograde axonal transport of BDNF and proNGF diminishes with age in basal forebrain cholinergic neurons. Neurobiol. Aging, 84: 131-140, https://doi.org/10.1016/j.neurobiolaging.2019.07.018 * uses XonaChips® (XC450) with rat basal forebrain or cortical neurons  https://www.ncbi.nlm.nih.gov/pubmed/31574357
Tags: basal forebrain cholinergic neurons, cortical neurons, rat, XC450

Van Laar, V. S., B. Arnold, E. H. Howlett, M. J. Calderon, C. M. St Croix, J. T. Greenamyre, L. H. Sanders and S. B. Berman, 2018. Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress. J Neurosci 38(34): 7505-7515. https://doi.org/10.1523/jneurosci.0541-18.2018
Tags: cortical neurons, rat, SND450, SND900

Westergard, T., Jensen, Brigid K., Wen, X., Cai, J., Kropf, E., Iacovitti, L., Pasinelli, P., Trotti, D., 2016. Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD. Cell Reports 17, 645-652. * uses Xona’s Silicone (PDMS) Devices (SND150) with primary rat cortical neurons https://doi.org/10.1016/j.celrep.2016.09.032
Tags: cortical neurons, primary, rat, SND150

Taylor, A. M., N. C. Berchtold, V. M. Perreau, C. H. Tu, N. Li Jeon and C. W. Cotman, 2009. Axonal mRNA in uninjured and regenerating cortical mammalian axons. The Journal of Neuroscience 29(15): 4697-4707. https://doi.org/10.1523/jneurosci.6130-08.2009
Tags: cortical neurons, injury, rat, SND900, Xona author

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