Latest News & Technotes
Xona introduces a new open compartment neuron culture device and microfluidic platform called the Innsbruck device. This Silicone (PDMS) Device is a compartmentalized microfluidic chamber with an enclosed center compartment and two open outer compartments.
Xona Microfluidics receives a 2-year phase I SBIR grant to develop in vitro assays using its patented technology for Alzheimer’s disease research.
Xona’s round microfluidic chambers were placed into 12-well plates increase throughput and sample size. Montage images of each well containing the microfluidic device illustrate how automated imaging can be performed in such a format.
Customize Neuronal Microenvironments with
Xona Microfluidic Devices
Xona Microfluidics® provides high quality microfluidic devices for compartmentalizing neurons.
Our expert team includes neuroscientists with critical experience designing and conducting research. Xona has been awarded numerous NIH grants and, in 2020, began offering contract research services.
Xona holds the original, exclusive license to sell compartmentalized microfluidic devices, originally described in Nature Methods (2005). Dr. Anne Taylor, an inventor, is Xona’s Chief Scientific Officer.
Our microfluidic devices enable the unique study of neuronal subcellular compartments and lead to the development of valuable in vitro models of the NMJ and other co-culture innervation models. Our devices are used extensively for Alzheimer’s disease, ALS, and Parkinson’s disease research.
Xona’s time-tested technology has been cited in over 1,000 publications. Many of these publications can be found on our publications page.
Both primary neurons and human iPSC-derived neurons can be easily cultured within our platforms. Neurons can be cultured for 21 or more days. Xona Microfluidics® sells both the original Silicone (PDMS) Devices as well as our newer XonaChips® which are made of optically transparent cyclic olefin copolymer.