Latest News & Technotes
The Meyer’s lab (Indiana University) grows retinal ganglion cells (RGCs) in XonaChips®
Paper Highlight! RGCs expressing a fluorescent protein were purified from human pluripotent stem cell (hPSC) -derived organoids and then grown within XonaChips®, as detailed in a recent 2021 publication Stem Cell Reports from Jason Meyer’s lab at Indiana University.
3D cultures in XonaChips® used for high profile Alzheimer’s disease study
Paper Highlight! An impressive paper in Cell Reports from the Tanzi lab uses XonaChips® to create 3D compartmentalized cultures. ELISA was used to quantify Aβ levels using media isolated from the axonal compartment.
Cellular model of human motor unit using XonaChips exhibits ALS disease hallmarks
Paper Highlight! The Van Den Bosch Lab (KU Leuven/VIB) creates in vitro human motor units using XonaChips®. These results were recently published in Stem Cell Reports April 2021.
Seeking collaborators!
Xona is actively looking for partners interested in screening/validating their target compound(s) using our cell-based tau mislocalization assay or similar assays for Alzheimer’s Disease (AD/ADRD) research. We have high content imaging capabilities and are planning to use 3D human iPSC-derived neuron cultures. Please contact us at info@xona.us to learn more. We are applying for a NIH/NIA SBIR for this development work.
See videos featuring neurons cultured in XonaChips®
Introducing XonaChips®
Use XonaChips® to Compartmentalize Primary Murine Neurons
Use XonaChips® to Compartmentalize Stem Cell Derived Neurons
FLUIDIC ISOLATION OF AXONS
WITH CUSTOMIZED MICROENVIRONMENTS
XONA MICROFLUIDICS offers a wide selection of devices for neuron cell culture.
The pre-assembled, easy to use XonaChip® offers a high quality, reproducible method for the
compartmentalization, fluidic isolation and improved organization of neuronal cultures.
They are especially great for culturing human stem cell-derived neurons.
The XonaChip® offers the researcher a novel method to isolate and grow axons, ultimately delivering the ability to study neuronal response to axonal damage due to disease or injury in an isolated fluidic environment.