Latest News & Technotes
Paper Highlight! RGCs expressing a fluorescent protein were purified from human pluripotent stem cell (hPSC) -derived organoids and then grown within XonaChips®, as detailed in a recent 2021 publication Stem Cell Reports from Jason Meyer’s lab at Indiana University.
Paper Highlight! An impressive paper in Cell Reports from the Tanzi lab uses XonaChips® to create 3D compartmentalized cultures. ELISA was used to quantify Aβ levels using media isolated from the axonal compartment.
Paper Highlight! The Van Den Bosch Lab (KU Leuven/VIB) creates in vitro human motor units using XonaChips®. These results were recently published in Stem Cell Reports April 2021.
Xona is actively looking for partners interested in screening/validating their target compound(s) using our cell-based tau mislocalization assay or similar assays for Alzheimer’s Disease (AD/ADRD) research. We have high content imaging capabilities and are planning to use 3D human iPSC-derived neuron cultures. Please contact us at firstname.lastname@example.org to learn more. We are applying for a NIH/NIA SBIR for this development work.
FLUIDIC ISOLATION OF AXONS
WITH CUSTOMIZED MICROENVIRONMENTS
XONA MICROFLUIDICS offers a wide selection of devices for neuron cell culture.
The pre-assembled, easy to use XonaChip® offers a high quality, reproducible method for the
compartmentalization, fluidic isolation and improved organization of neuronal cultures.
They are especially great for culturing human stem cell-derived neurons.
The XonaChip® offers the researcher a novel method to isolate and grow axons, ultimately delivering the ability to study neuronal response to axonal damage due to disease or injury in an isolated fluidic environment.